Objective: To investigate the effect of factors influencing palliative care decision-making choices, in order to improve palliative care awareness and promote the use of palliative care in the medical treatment of patients at the end of life. Methods: Read the literature, prepared a questionnaire, and conducted a questionnaire survey of residents with different health statuses using convenience sampling methods. Results: The gender difference was that males were more likely to be cared for by friends (13 males 33.3%, 9 females 12.9%, x2 =6.518,p=0.011) and unattended (4 males 10.3%, 1 female 1.4%, x2 =4.460,p=0.035); compared to other health statuses (2 healthy 4.3%, 7 sub-healthy 15.6%, 0 sick 0.0%) most of the people with incurable diseases (3 people 75%) do not want to know the truth about their diseases, this result x2 =21.483,p=0.000; and there is no statistically significant difference between the gender and health status in the selection of palliative care (results x2 =1.517,p=0.218; x2 =7.530,p=0.057;respectively).Conclusion: How to make residents scientifically understand and accept palliative care needs to be resolved urgently, to improve the awareness of palliative care, fully understand the factors affecting the choice of palliative care decision-making is beneficial to the promotion of its clinical application and improve the quality of life of patients at the end of life.